How vitamin D deficiency is linked to chronic pain

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By nifwlseirff

Sunlight provides some vitamin D, but not enough for chronic pain sufferers.
Sunlight provides some vitamin D, but not enough for chronic pain sufferers.

Scientists are still untangling the riddle of chronic pain. Everyone who suffers chronic pain has different symptoms and triggers. A treatment that works for one person, may not work for another person.

It is frustrating for the chronic pain sufferers - they must test a large number of treatments to find the ones that help them the most. And this may change over time. It's also frustrating for the scientists and doctors, as there seems to be no single cause and therefore no single treatment.

In the last 5 years, increasingly more research has been performed into vitamin D levels in sufferers of chronic pain, specifically those with fibromyalgia syndrome. Some of these studies have shown that those with chronic pain have reduced vitamin D levels, but they don't yet understand why.

Although it has not yet been proven that increased vitamin D intake reduces pain, the longer term benefits of maintaining a stable normal level of vitamin D, after being diagnosed with a deficiency, is a good reason that doctors recommend that chronic pain sufferers take supplements.

Elliot Krane: The mystery of chronic pain

Chronic pain

Pain becomes chronic when it persists for more than 3-6 months, although some doctors classify it as chronic pain only after 12 months. There is often no obvious physical sign of the pain, and sufferers are often told it's all in their head.

Chronic pain can be caused by such a multitude of diseases and physical problems. Nerve problems, brain chemistry problems, inflammation, breakages, viruses, even past injuries - almost anything can cause long term pain.

Each person's journey through diagnosing and living with chronic pain, finding treatments that help them manage, will be different. Some researchers are looking at how vitamins may affect how a person's brain perceives pain, as it seems that chronic pain sufferers often have different levels of vitamins to people who are 'healthy'.

There are theories that vitamin D is used faster for those in chronic pain as their immune systems are under constant stress. But this has not yet been proven.

Vitamin D3
Vitamin D3

Vitamin D

Vitamin D is important for healthy bone growth and repair. It plays an important role in preventing osteoporosis as we age.

Levels are tested by taking a blood sample. Each laboratory may use a different testing method, and the 'normal' range for reference is included in the blood test report.

Vitamin D is created in the kidneys, from foods that we eat. Foods higher in vitamin D include:

  • fatty fish such as catfish, salmon, mackerel, sardines, trout, tuna, and oysters
  • fish liver oils
  • shiitake, portabella and other types of mushrooms, when grown in sunlight or under UV lights
  • whole eggs

Recommended vitamin D intake

The recommended intake from food or supplements varies between countries. The range of recommended levels start from the European Union's 200 IU/Day (5.0 μg/day), to Canada's recommendation for those over 70 to have 800 IU/day (20 μg/day).

For adults, including those who are pregnant or breastfeeding, the upper 'safe' limit is set at 4,000 IU (100 μg/day). Taking more than 50,000 IU/day (250µg/day) risks vitamin D poisoning, however, this is unlikely to happen without tablet supplementation.

In recent years, many health professionals have claimed that vitamin D deficiency is on the rise, thanks to longer working hours spent indoors.

Vitamin D deficiency

When a person's diet does not contain enough vitamin D, and they do not have enough skin-exposure to sunlight, then vitamin D levels may decline, and eventually become deficient.

A vitamin D deficiency can cause bone demineralisation (rickets in children, osteomalacia in adults), osteoporosis, as well as weak, aching and twitching muscles. Scientific American published an article linking vitamin D deficiency to an increase in risk of colds and the flu in winter, especially for those with underlying respiratory problems. Other health professionals have claimed that a variety of diseases are caused by or made worse by low levels of vitamin D.

Some daily skin exposure sunlight is important for the body to manufacture a healthy level of vitamin D, but some care must be taken.

How many hours of sunlight is your skin exposed to each day on average?

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Vitamin D from sunlight

Humans create vitamin D in the skin when exposed to 'sufficient' sunlight (UVB). This occurs usually when the UV index is above 3, which is more commonly in summer and late spring/early autumn or year-round in tropical areas.

Studies show that reduced exposure to sunlight causes a decrease in vitamin D levels. In modern society, many people work inside during the day, and are exposed to very little sunlight, resulting in the increase in lower levels of vitamin D.

Anti-cancer societies encourage the constant use of high-protection sunscreen lotions, as skin cancer rates rise worldwide. However, as sunscreen blocks UV rays and prevents vitamin D production in the skin, this may contribute to the growing number of vitamin D deficient people. It is difficult to determine where the happy medium lies.

It has also been shown that sunlight is important for those suffering from depression. Many chronic pain sufferers also deal with depression - being in pain all of the time is not easy to handle.

The link between vitamin D and pain

It is not known if the chronic pain causes a reduction in vitamin D levels, or whether the low levels cause more pain. It is not even proven that such a direct link in either direction exists, yet research seems to indicate there is some relationship between long-term pain and vitamin D.

An Australian study and the Mayo clinic have both suggested that supplementing vitamin D helps to reduce or stop the wind-up response in chronic pain sufferers, where the pain-threshold is lowered by constant pain signals over-sensitizing pain receptors in the brain. This may be useful for those suffering fibromyalgia, known for having a particularly strong wind-up response.

Although many studies have not proven that vitamin D supplementation helps chronic pain, supplementation with vitamin D3 is inexpensive. Doctors may choose to prescribe supplements for those who have tested low levels, both for the possible pain reduction, and for the longer term protection of bone health.

Sunset in Melbourne, Australia.
Sunset in Melbourne, Australia.

Disclaimer

I am not a medical professional. If you have pain of any kind, or are considering supplementing your diet with vitamin D tablets, please contact your doctor.

I have been diagnosed with multiple chronic pain conditions, including fibromyalgia, adenomyosis, and various other inflammatory and nerve conditions. I also have an extremely low (and difficult to raise) vitamin D level, which some doctors and pharmacists had mentioned was linked to the chronic pain conditions.

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Comments

izettl profile image

izettl Level 6 Commenter 5 months ago

Great informative article on this topic.

nifwlseirff profile image

nifwlseirff Hub Author 5 months ago

Thank you izettl!

I was prompted to research the connection, when chemists and doctors in three different countries were not surprised that I have low D levels, as I suffer chronic pain.

Night Magic profile image

Night Magic 5 months ago

Excellent Hub --- good info and resources. I take 2000 IU of vitamin D3 each day. It's really helped me.

nifwlseirff profile image

nifwlseirff Hub Author 5 months ago

Thanks Night Magic! I take large doses daily, and blood tests are slowly improving. But I haven't noticed any direct improvement of pain. However, I will keep taking the tablets, to help with my bones in the longer term!

Rachel Richmond profile image

Rachel Richmond Level 4 Commenter 4 months ago

Hello nifwlseirff - I like and have to go with your observations/research on Vit. D. Too many who begin to get out into the sun or take a supplement feel better and sleep better. LOL...They were happier and easier to work with...

nifwlseirff profile image

nifwlseirff Hub Author 4 months ago

Thanks Rachel! I don't know whether it's because they were out and about, getting a little exercise, or taking more care of their health, or because the extra vitamin D was lessening their pain. But in any case, if it works, then it is good!

AliciaC profile image

AliciaC Level 7 Commenter 3 months ago

Thank you for the information, nifwiseirff. I know someone who suffers from fibromyalgia and chronic pain. I'll ask her about her vitamin D intake. Good luck with managing your pain.

nifwlseirff profile image

nifwlseirff Hub Author 3 months ago

Thank you AliciaC! I hope this info can help your friend.

brilliantenergy profile image

brilliantenergy 6 weeks ago

your science is a little weak. you skipped over the critical linkage to endocrinology

nifwlseirff profile image

nifwlseirff Hub Author 6 weeks ago

Brilliantenergy - the endocrine system, how vitamin D is converted and used within it, and how the system affects/is affected by chronic pain, are all still not well understood or studied by medical professionals. I'd love to write a detailed review of the medical literature, but this is not the appropriate place for that style of writing.

ekkej 3 weeks ago

How do you know if you are deficient in Vitamin D? I have intense persistent fatigue but there is nothing wrong with my blood tests does that mean it isn't Vit D?

nifwlseirff profile image

nifwlseirff Hub Author 3 weeks ago

ekkej - Other deficiencies can cause constant fatigue, especially also the B vitamin levels. A blood test is the only way to know for sure if you are deficient in D, and if your blood test level of D is ok, then I believe that is not what is causing the tiredness. Perhaps you could get your B levels and thyroid checked? (Doctors are always testing my thyroid, because of chronic exhaustion/illnesses, but the results are always fine). Good luck!

ekkej 3 weeks ago

Thanks much for replying, I see this article was written 4 months ago. It is good advice. I'm sorry that you have chronic exhaustion. And also I think it is the worst when the tests seem like everything should be fine, and you can not work out the reasons for the symptom. Good luck also to you too.

nifwlseirff profile image

nifwlseirff Hub Author 3 weeks ago

ekkej - thank you! I'm glad the advice was useful (I do update my articles from time to time, especially if new research is released).

I agree, when tests come back without showing anything wrong, it's very frustrating. My vitamin D levels are slowly increasing, thanks to supplements, and my next test is in a couple of weeks. I haven't seen a difference in tiredness, but I'm happy my bones are a bit more protected with the higher D levels!

ekkej 3 weeks ago

I saw my doctor this morning to asked about my blood tests to get more details. I found that she did not tested Vit D or B at all. So my "normal" results of all tests does not include it! I asked why. She said that she had a letter from a government department and she had been testing too many D levels compared to other doctors. For the B vitamin, she said it is only vegetarians who can be deficient. It means, be careful to tell your doctor to test for each thing you need. Just saying "please test everything!", as I did, will might not work. So hard to find doctors who will explain to me and most does not listen at all.

Anyway that is enough post on your good article. Thank you again.

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